Studies on 4-Chloropyrido [2, 3-d] pyrimidine and Pyrido [2, 3-d] pyrimidine
نویسندگان
چکیده
منابع مشابه
Sequence specificity of the non-natural pyrido[2, 3-d]pyrimidine nucleoside in triple helix formation
The non-natural pyrido[2,3-d]pyrimidine nucleoside F, which pairs preferentially with guanine (G) and adenine (A) within double-helical DNA, recognizes with high selectivity AT base pairs within triple-helical complexes. These observations suggest that F may exist in different tautomeric forms within double-helical and triple-helical complexes. Analysis of the base stacking properties of this e...
متن کامل2-(3-Methoxyphenoxy)pyrimidine
In the title compound, C(11)H(10)N(2)O(2), the benzene ring faces towards one of the pyrimidine N atoms, and is almost orthogonal to the plane through the pyrimidine ring [dihedral angle = 84.40 (14)°]. In the crystal, the presence of C-H⋯π and π-π [centroid-centroid separation = 3.7658 (18) Å] inter-actions leads to a supra-molecular array in the ac plane. The layers thus formed inter-digitate...
متن کامل2-Methylsulfanyl-4-(3-pyridyl)pyrimidine
In the title compound, C(10)H(9)N(3)S, the dihedral angle between the aromatic rings is 8.09 (14)°. In the crystal, a C-H⋯N interaction links the molecules, forming chains.
متن کاملStudies on 4-aminopyrazolo(3, 4-d)pyrimidine: growth inhibition and relief in Neurospora crassa.
An analogue of adenine, 4-aminopyrazolo(3,4d)pyrimidine (4-APP), has recently been shown to be a potential antineoplastic agent. Skipper, Robins, and Thomson (1955) demonstrated that the growth of an adenocarcinoma and two leukemias of the mouse was inhibited or retarded by the administration of 4-APP. Hsu, Robins and Cheng (1956) showed that 4-aminopyrazolo(3,4d)pyrimidine exerts differential ...
متن کاملElectron as potential and green catalyst in the multicomponent synthesis of pyrano [2, 3-d] pyrimidine derivatives
An electroorganic reaction for the synthesis of 7-amino-2, 4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-pyrano[2, 3-d] pyrimidine-6-carbonitrile and ethyl-7-amino-2, 4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-pyrano[2, 3-d] pyrimidine-6-carboxylate derivatives are described, using an electrogenerated base of the anion of malonitrile or ethylcyanoacetate. This one-pot, three-component condensation of an a...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1970
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.18.1457